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碱性成纤维细胞生长因子
药物基本信息
通用名:碱性成纤维细胞生长因子
临床用途:应用于烧伤和皮肤损伤
市场需求
碱性成纤维细胞生长因子(bFGF,FGF2或FGF-β)是成纤维细胞生长因子家族中的一员。bFGF是一种单链多肽生长因子,在促进细胞增殖过程中起着重要作用。在体外,bFGF对内皮细胞具有的趋化和促有丝分裂剂的作用,并且能够促进神经的分化,存活和再生。同时也可以抑制细胞凋亡,加速伤口愈合并诱导血管再生。在中胚层和神经外胚层等多种类型的细胞中, bFGF亦能非常有效地诱导DNA的合成。
 
The basic information of drug
common name: Basic fibroblast growth factor
Clinical use: treatment of burns and skin damage
Market demand
bFGF(bFGF,FGF2 or FGF-β)is a member of the fibroblast growth factor family. bFGF is a single chain polypeptide growth factor that plays an important role in promoting cell proliferation. In vitro, bFGF has an effect on chemotaxis and mitogenic agents on endothelial cells, and can promote neural differentiation, survival and regeneration. At the same time, it also can inhibit cell apoptosis, accelerate wound healing and induce vascular regeneration. In the mesoderm and neuroectoderm and other types of cells, bFGF can also be very effective in inducing DNA synthesis.